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Functional Analysis of Bacteriophage Immunity through a Type I-E CRISPR-Cas System in Vibrio cholerae and Its Application in Bacteriophage Genome Engineering

The classical and El Tor biotypes of Vibrio cholerae serogroup O1, the etiological agent of cholera, are responsible for the sixth and seventh (current) pandemics, respectively. A genomic island (GI), GI-24, previously identified in a classical biotype strain of V. cholerae, is predicted to encode c...

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Bibliografske podrobnosti
izdano v:J Bacteriol
Main Authors: Box, Allison M., McGuffie, Matthew J., O'Hara, Brendan J., Seed, Kimberley D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719448/
https://ncbi.nlm.nih.gov/pubmed/26598368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00747-15
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