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Ferritin synthesis is controlled by iron-dependent translational derepression and by changes in synthesis/transport of nuclear ferritin RNAs.

Ferritin synthesis, maintained at a very low basal rate when extracellular iron levels are low, is elevated up to 50-fold when iron levels are increased. Previous examinations of this iron-dependent activation have concluded that changes in ferritin synthesis results from selective translational act...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Coulson, R M, Cleveland, D W
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47192/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8356063/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.16.7613
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