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Replication-Competent Influenza Virus and Respiratory Syncytial Virus Luciferase Reporter Strains Engineered for Co-Infections Identify Antiviral Compounds in Combination Screens

Myxoviruses such as influenza A virus (IAV) and respiratory syncytial virus (RSV) are major human pathogens, mandating the development of novel therapeutics. To establish a high-throughput screening protocol for the simultaneous identification of pathogen- and host-targeted hit candidates against ei...

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Dettagli Bibliografici
Pubblicato in:Biochemistry
Autori principali: Yan, Dan, Weisshaar, Marco, Lamb, Kristen, Chung, Hokyung K, Lin, Michael Z, Plemper, Richard K
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719150/
https://ncbi.nlm.nih.gov/pubmed/26307636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00623
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