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Pulmonary instillation of MWCNT increases lung permeability, decreases gp130 expression in the lungs, and initiates cardiovascular IL-6 transsignaling

Pulmonary instillation of multiwalled carbon nanotubes (MWCNT) has the potential to promote cardiovascular derangements, but the mechanisms responsible are currently unclear. We hypothesized that exposure to MWCNT would result in increased epithelial barrier permeability by 24 h postexposure and ini...

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Foilsithe in:Am J Physiol Lung Cell Mol Physiol
Main Authors: Thompson, Leslie C., Holland, Nathan A., Snyder, Ryan J., Luo, Bin, Becak, Daniel P., Odom, Jillian T., Harrison, Benjamin S., Brown, Jared M., Gowdy, Kymberly M., Wingard, Christopher J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Physiological Society 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719050/
https://ncbi.nlm.nih.gov/pubmed/26589480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00384.2014
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