Pulmonary instillation of MWCNT increases lung permeability, decreases gp130 expression in the lungs, and initiates cardiovascular IL-6 transsignaling

Pulmonary instillation of multiwalled carbon nanotubes (MWCNT) has the potential to promote cardiovascular derangements, but the mechanisms responsible are currently unclear. We hypothesized that exposure to MWCNT would result in increased epithelial barrier permeability by 24 h postexposure and ini...

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Udgivet i:Am J Physiol Lung Cell Mol Physiol
Main Authors: Thompson, Leslie C., Holland, Nathan A., Snyder, Ryan J., Luo, Bin, Becak, Daniel P., Odom, Jillian T., Harrison, Benjamin S., Brown, Jared M., Gowdy, Kymberly M., Wingard, Christopher J.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2015
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719050/
https://ncbi.nlm.nih.gov/pubmed/26589480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00384.2014
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