Regulatory Crosstalk by Protein Kinases on CFTR Trafficking and Activity

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) is a member of the ATP binding cassette (ABC) transporter superfamily that functions as a cAMP-activated chloride ion channel in fluid-transporting epithelia. There is abundant evidence that CFTR activity (i.e., channel opening and closing)...

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Bibliographische Detailangaben
Veröffentlicht in:Front Chem
Hauptverfasser: Farinha, Carlos M., Swiatecka-Urban, Agnieszka, Brautigan, David L., Jordan, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2016
Schlagworte:
Chemistry
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718993/
https://ncbi.nlm.nih.gov/pubmed/26835446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2016.00001
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