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Amyloid β Peptide Induces Apoptosis Through P2X7 Cell Death Receptor in Retinal Cells: Modulation by Marine Omega-3 Fatty Acid DHA and EPA

Retinal Müller glial cells have already been implicated in age-related macular degeneration (AMD). AMD is characterized by accumulation of toxic amyloid-β peptide (Aβ); the question we raise is as follows: is P2X7 receptor, known to play an important role in several degenerative diseases, involved i...

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Detalhes bibliográficos
Publicado no:Appl Biochem Biotechnol
Main Authors: Wakx, Anaïs, Dutot, Mélody, Massicot, France, Mascarelli, Frédéric, Limb, G. Astrid, Rat, Patrice
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718936/
https://ncbi.nlm.nih.gov/pubmed/26467741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12010-015-1878-6
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