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Synthesis and photochemical properties of PEGylated coumarin-caged ceramides for cell studies

Caged ceramide analogues (C6-, C16-, C18-, C22- and C24-Cer) have been prepared by introducing a hydrophilic coumarin-based cage bearing a short polyethylene glycol (PEG) chain. (6-Bromo-7-mTEGylated-coumarin-4-yl)methyl (Btc) caged ceramide showed efficient photo-uncaging to release the parent cera...

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Detalhes bibliográficos
Publicado no:Chem Phys Lipids
Main Authors: Kim, Young Ah, Day, Jenna, Lirette, Carol Ann, Costain, Willard J., Johnston, Linda J., Bittman, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718835/
https://ncbi.nlm.nih.gov/pubmed/26200920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chemphyslip.2015.07.006
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