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Effects of PCB126 and PCB153 on telomerase activity and telomere length in undifferentiated and differentiated HL-60 cells

PCBs are persistent organic pollutants with carcinogenic, immune- and developmental toxicity. This suggests that they may interfere with normal cell maturation. Cancer and stem/progenitor cells have telomerase activity to maintain and protect the chromosome ends, but lose this activity during differ...

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Detalhes bibliográficos
Publicado no:Environ Sci Pollut Res Int
Main Authors: Xin, Xing, Senthilkumar, PK, Schnoor, Jerald L., Ludewig, Gabriele
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718801/
https://ncbi.nlm.nih.gov/pubmed/26330309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11356-015-5187-y
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