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Nanoemulsion formulations for anti-cancer agent piplartine – characterization, toxicological, pharmacokinetics and efficacy studies

Piplartine (PL) is an alkaloid found in black-pepper and known for its anticancer activity, however, due to poor solubility and lack of proper formulation, its use for oral administration is a challenge. The objective of this study was to formulate PL into nanoemulsion drug delivery system for oral...

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Detalhes bibliográficos
Publicado no:Int J Pharm
Main Authors: Fofaria, Neel M., Qhattal, Hussaini Syed Sha, Liu, Xinli, Srivastava, Sanjay K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718800/
https://ncbi.nlm.nih.gov/pubmed/26642946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2015.11.045
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