Transgenic mice containing a 248-kb yeast artificial chromosome carrying the human beta-globin locus display proper developmental control of human globin genes.

Lignende værker

• Use of yeast artificial chromosomes (YACs) in studies of mammalian development: production of beta-globin locus YAC mice carrying human globin developmental mutants.
  af: Peterson, K R, et al.
  Udgivet: (1995)
• Effect of deletion of 5'HS3 or 5'HS2 of the human beta-globin locus control region on the developmental regulation of globin gene expression in beta-globin locus yeast artificial chromosome transgenic mice.
  af: Peterson, K R, et al.
  Udgivet: (1996)
• The human beta-globin locus activation region alters the developmental fate of a human fetal globin gene in transgenic mice.
  af: Enver, T, et al.
  Udgivet: (1989)
• Developmental regulation of human gamma-globin genes in transgenic mice.
  af: Stamatoyannopoulos, G, et al.
  Udgivet: (1993)
• Genome Architecture of the Human β-Globin Locus Affects Developmental Regulation of Gene Expression
  af: Harju, Susanna, et al.
  Udgivet: (2005)