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Diabetes-associated cardiac fibrosis: cellular effectors, molecular mechanisms and therapeutic opportunities

Both type 1 and type 2 diabetes are associated with cardiac fibrosis that may reduce myocardial compliance, contribute to the pathogenesis of heart failure, and trigger arrhythmic events. Diabetes-associated fibrosis is mediated by activated cardiac fibroblasts, but may also involve fibrogenic actio...

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Detalhes bibliográficos
Publicado no:J Mol Cell Cardiol
Main Authors: Russo, Ilaria, Frangogiannis, Nikolaos G
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718740/
https://ncbi.nlm.nih.gov/pubmed/26705059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2015.12.011
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