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SPARC Expression Is Selectively Suppressed in Tumor Initiating Urospheres Isolated from As(+3)- and Cd(+2)-Transformed Human Urothelial Cells (UROtsa) Stably Transfected with SPARC

BACKGROUND: This laboratory previously analyzed the expression of SPARC in the parental UROtsa cells, their arsenite (As(+3)) and cadmium (Cd(+2))-transformed cell lines, and tumor transplants generated from the transformed cells. It was demonstrated that SPARC expression was down-regulated to backg...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Slusser-Nore, Andrea, Larson-Casey, Jennifer L., Zhang, Ruowen, Zhou, Xu Dong, Somji, Seema, Garrett, Scott H., Sens, Donald A., Dunlevy, Jane R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718619/
https://ncbi.nlm.nih.gov/pubmed/26783756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147362
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