Identification of Novel HLA-A*24:02-Restricted Epitope Derived from a Homeobox Protein Expressed in Hematological Malignancies

The homeobox protein, PEPP2 (RHOXF2), has been suggested as a cancer/testis (CT) antigen based on its expression pattern. However, the peptide epitope of PEPP2 that is recognized by cytotoxic T cells (CTLs) is unknown. In this study, we revealed that PEPP2 gene was highly expressed in myeloid leukem...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Matsushita, Maiko, Otsuka, Yohei, Tsutsumida, Naoya, Tanaka, Chiaki, Uchiumi, Akane, Ozawa, Koji, Suzuki, Takuma, Ichikawa, Daiju, Aburatani, Hiroyuki, Okamoto, Shinichiro, Kawakami, Yutaka, Hattori, Yutaka
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718592/
https://ncbi.nlm.nih.gov/pubmed/26784514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146371
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