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Identification of CD4 and major histocompatibility complex functional peptide sites and their homology with oligopeptides from human immunodeficiency virus type 1 glycoprotein gp120: role in AIDS pathogenesis.

CD4 molecules interact with class II major histocompatibility complex molecules as a critical costimulatory signal in CD4+ cell immune activation. CD4 also recognizes a specific region of the human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein gp120 forming a binding site for early sta...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Zagury, J F, Bernard, J, Achour, A, Astgen, A, Lachgar, A, Fall, L, Carelli, C, Issing, W, Mbika, J P, Picard, O
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47184/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8356059/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.16.7573
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