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Cap dependent translation contributes to resistance of myeloma cells to bortezomib
Multiple myeloma (MM) is the second most predominant blood malignancy. Proteasome inhibitors like bortezomib have increased life expectancy, but eventually patients develop resistance to therapy. It was proposed that bortezomib acts through the induction of the Unfolded Protein Response (UPR), i.e.,...
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| Veröffentlicht in: | Translation (Austin) |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4718057/ https://ncbi.nlm.nih.gov/pubmed/26824026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trla.27245 |
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