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Cap dependent translation contributes to resistance of myeloma cells to bortezomib

Multiple myeloma (MM) is the second most predominant blood malignancy. Proteasome inhibitors like bortezomib have increased life expectancy, but eventually patients develop resistance to therapy. It was proposed that bortezomib acts through the induction of the Unfolded Protein Response (UPR), i.e.,...

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Detalhes bibliográficos
Publicado no:Translation (Austin)
Main Authors: Mancino, Marilena, Grosso, Stefano, Terragna, Carolina, Borsi, Enrica, Cavo, Michele, Biffo, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718057/
https://ncbi.nlm.nih.gov/pubmed/26824026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trla.27245
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