Environmental cold exposure increases blood flow and affects pain sensitivity in the knee joints of CFA-induced arthritic mice in a TRPA1-dependent manner

BACKGROUND: The effect of cold temperature on arthritis symptoms is unclear. The aim of this study was to investigate how environmental cold affects pain and blood flow in mono-arthritic mice, and examine a role for transient receptor potential ankyrin 1 (TRPA1), a ligand-gated cation channel that c...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Fernandes, Elizabeth S., Russell, Fiona A., Alawi, Khadija M., Sand, Claire, Liang, Lihuan, Salamon, Robin, Bodkin, Jennifer V., Aubdool, Aisah A., Arno, Matthew, Gentry, Clive, Smillie, Sarah-Jane, Bevan, Stuart, Keeble, Julie E., Malcangio, Marzia, Brain, Susan D.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718045/
https://ncbi.nlm.nih.gov/pubmed/26754745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0905-x
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