High-mobility group box 1 potentiates antineutrophil cytoplasmic antibody-inducing neutrophil extracellular traps formation

BACKGROUND: Recent studies found that the circulating high-mobility group box 1 (HMGB1) levels could reflect the disease activity of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). HMGB1 could prime neutrophils by increasing ANCA antigens translocation for ANCA-mediated respi...

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Pubblicato in:Arthritis Res Ther
Autori principali: Ma, Yun-Hua, Ma, Tian-tian, Wang, Chen, Wang, Huan, Chang, Dong-Yuan, Chen, Min, Zhao, Ming-Hui
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718033/
https://ncbi.nlm.nih.gov/pubmed/26739852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0903-z
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