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Macrophage‐mediated cholesterol handling in atherosclerosis

Formation of foam cells is a hallmark at the initial stages of atherosclerosis. Monocytes attracted by pro‐inflammatory stimuli attach to the inflamed vascular endothelium and penetrate to the arterial intima where they differentiate to macrophages. Intimal macrophages phagocytize oxidized low‐densi...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Chistiakov, Dimitry A., Bobryshev, Yuri V., Orekhov, Alexander N.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717859/
https://ncbi.nlm.nih.gov/pubmed/26493158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12689
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