Dysregulation of Glucose Homeostasis Following Chronic Exogenous Administration of Leptin in Healthy Sprague-Dawley Rats

INTRODUCTION: Impaired glucose utilization is seen in chronic hyperleptinaemia associated conditions such as obesity and type 2 diabetes mellitus. It is unclear if this impaired glucose utilization is due to the effect of persistent hyperleptinaemia on insulin secretion from the beta cells of pancre...

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Bibliografiske detaljer
Udgivet i:J Clin Diagn Res
Main Authors: Wjidan, Khalil, Ibrahim, Effendi, Caszo, Brinnell, Gnanou, Justin, Singh, Harbindarjeet
Format: Artigo
Sprog:Inglês
Udgivet: JCDR Research and Publications (P) Limited 2015
Fag:
Internal Medicine Section
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717792/
https://ncbi.nlm.nih.gov/pubmed/26816939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7860/JCDR/2015/15594.7003
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