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The molecular targets of approved treatments for pulmonary arterial hypertension

Until recently, three classes of medical therapy were available for the treatment of pulmonary arterial hypertension (PAH)—prostanoids, endothelin receptor antagonists and phosphodiesterase type 5 (PDE5) inhibitors. With the approval of the soluble guanylate cyclase stimulator riociguat, an addition...

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Détails bibliographiques
Publié dans:Thorax
Auteurs principaux: Humbert, Marc, Ghofrani, Hossein-Ardeschir
Format: Artigo
Langue:Inglês
Publié: BMJ Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717417/
https://ncbi.nlm.nih.gov/pubmed/26219978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2015-207170
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