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The molecular targets of approved treatments for pulmonary arterial hypertension

Until recently, three classes of medical therapy were available for the treatment of pulmonary arterial hypertension (PAH)—prostanoids, endothelin receptor antagonists and phosphodiesterase type 5 (PDE5) inhibitors. With the approval of the soluble guanylate cyclase stimulator riociguat, an addition...

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Detalles Bibliográficos
Publicado en:Thorax
Autores principales: Humbert, Marc, Ghofrani, Hossein-Ardeschir
Formato: Artigo
Lenguaje:Inglês
Publicado: BMJ Publishing Group 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717417/
https://ncbi.nlm.nih.gov/pubmed/26219978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2015-207170
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