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Regional metabolic heterogeneity of the hippocampus is nonuniformly impacted by age and caloric restriction

The hippocampus is critical for cognition and memory formation and is vulnerable to age‐related atrophy and loss of function. These phenotypes are attenuated by caloric restriction (CR), a dietary intervention that delays aging. Here, we show significant regional effects in hippocampal energy metabo...

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Dettagli Bibliografici
Pubblicato in:Aging Cell
Autori principali: Martin, Stephen A., DeMuth, Tyler M., Miller, Karl N., Pugh, Thomas D., Polewski, Michael A., Colman, Ricki J., Eliceiri, Kevin W., Beasley, Timothy Mark, Johnson, Sterling C., Anderson, Rozalyn M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717265/
https://ncbi.nlm.nih.gov/pubmed/26521867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12418
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