Age‐related changes in murine myometrial transcript profile are mediated by exposure to the female sex hormones

In humans, the risk of operative first delivery increases linearly with maternal age. We previously hypothesized that prolonged, cyclical, prepregnancy exposure to estrogen and progesterone contributes to uterine aging. Here, we test this hypothesis. Myometrium was obtained from four groups of virgi...

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Veröffentlicht in:Aging Cell
Hauptverfasser: Chong, Hsu P., Cordeaux, Yolande, Ranjan, Yorain Sri, Richardson, Sylvia, Liquet, Benoit, Smith, Gordon C. S., Charnock‐Jones, David Stephen
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717263/
https://ncbi.nlm.nih.gov/pubmed/26490259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12406
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