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Using measures of single‐cell physiology and physiological state to understand organismic aging

Genetically identical organisms in homogeneous environments have different lifespans and healthspans. These differences are often attributed to stochastic events, such as mutations and ‘epimutations’, changes in DNA methylation and chromatin that change gene function and expression. But work in the...

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Опубликовано в: :Aging Cell
Главные авторы: Mendenhall, Alexander, Driscoll, Monica, Brent, Roger
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717262/
https://ncbi.nlm.nih.gov/pubmed/26616110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12424
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