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Stable expression of human cytochrome P450 2D6*10 in HepG2 cells
AIM: Over 90% of drugs are metabolized by the cytochrome P-450 (CYP) family of liver isoenzymes. The most important enzymes are CYP1A2, 3A4, 2C9/19, 2D6 and 2E1. Although CYP2D6 accounts for < 2% of the total CYP liver enzyme content, it mediates metabolism in almost 25% of drugs. In order to stu...
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| Publicado en: | World J Gastroenterol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Baishideng Publishing Group Inc
2004
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4717011/ https://ncbi.nlm.nih.gov/pubmed/14716830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v10.i2.234 |
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