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Hypomethylation of the MMP7 promoter and increased expression of MMP7 distinguishes the basal-like breast cancer subtype from other triple-negative tumors

Identification of novel targets for the treatment of basal-like breast cancer is essential for improved outcomes in patients with this disease. This study investigates the association of MMP7 expression and MMP7 promoter methylation with subtype and outcome in breast cancer patient cohorts. Immunohi...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res Treat
Main Authors: Sizemore, Steven T., Sizemore, Gina M., Booth, Christine N., Thompson, Cheryl L., Silverman, Paula, Bebek, Gurkan, Abdul-Karim, Fadi W., Avril, Stefanie, Keri, Ruth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4716673/
https://ncbi.nlm.nih.gov/pubmed/24847890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-014-2989-4
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