BAX inhibitor-1 is a Ca(2+) channel critically important for immune cell function and survival

The endoplasmic reticulum (ER) serves as the major intracellular Ca(2+) store and has a role in the synthesis and folding of proteins. BAX (BCL2-associated X protein) inhibitor-1 (BI-1) is a Ca(2+) leak channel also implicated in the response against protein misfolding, thereby connecting the Ca(2+)...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Lisak, D, Schacht, T, Gawlitza, A, Albrecht, P, Aktas, O, Koop, B, Gliem, M, Hofstetter, H H, Zanger, K, Bultynck, G, Parys, J B, De Smedt, H, Kindler, T, Adams-Quack, P, Hahn, M, Waisman, A, Reed, J C, Hövelmeyer, N, Methner, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4716298/
https://ncbi.nlm.nih.gov/pubmed/26470731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.115
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