Phase 2, randomised placebo-controlled trial to evaluate the efficacy and safety of an anti-GM-CSF antibody (KB003) in patients with inadequately controlled asthma

OBJECTIVES: We wished to evaluate the effects of an antigranulocyte-macrophage colony-stimulating factor monoclonal antibody (KB003) on forced expiratory volume in 1 s (FEV(1)), asthma control and asthma exacerbations in adult asthmatics inadequately controlled by long-acting bronchodilators and inh...

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Vydáno v:BMJ Open
Hlavní autoři: Molfino, Nestor A, Kuna, Piotr, Leff, Jonathan A, Oh, Chad K, Singh, Dave, Chernow, Marlene, Sutton, Brian, Yarranton, Geoffrey
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2016
Témata:
Respiratory Medicine
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4716197/
https://ncbi.nlm.nih.gov/pubmed/26739717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2015-007709
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