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Microenvironment interactions and B-cell receptor signaling in Chronic Lymphocytic Leukemia: implications for disease pathogenesis and treatment

Chronic Lymphocytic Leukemia (CLL) is a malignancy of mature B lymphocytes which are highly dependent on interactions with the tissue microenvironment for their survival and proliferation. Critical components of the microenvironment are monocyte-derived nurselike cells (NLCs), mesenchymal stromal ce...

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Veröffentlicht in:Biochim Biophys Acta
Hauptverfasser: ten Hacken, Elisa, Burger, Jan A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715999/
https://ncbi.nlm.nih.gov/pubmed/26193078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2015.07.009
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