PD-1 blunts the function of ovarian tumor-infiltrating dendritic cells by inactivating NF-κB

The PD-1:PD-L1 immune signaling axis mediates suppression of T cell-dependent tumor immunity. PD-1 expression was recently found to be upregulated on tumor-infiltrating murine (CD11c+CD11b+CD8−CD209a+) and human (CD1c+CD19−) myeloid dendritic cells (TIDC), an innate immune cell type also implicated...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Karyampudi, Lavakumar, Lamichhane, Purushottam, Krempski, James, Kalli, Kimberly R., Behrens, Marshall D., Vargas, Doris M., Hartmann, Lynn C, Janco, Jo Marie T, Dong, Haidong, Hedin, Karen E, Dietz, Allan B., Goode, Ellen L., Knutson, Keith L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715980/
https://ncbi.nlm.nih.gov/pubmed/26567141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0748
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados