Neuropilin-2 Regulates Endosome Maturation and EGFR trafficking to Support Cancer Cell Pathobiology

Neuropilin-2 (NRP2) is a non-tyrosine kinase receptor frequently overexpressed in various malignancies where it has been implicated in promoting many protumorigenic behaviors, such as imparting therapeutic resistance to metastatic cancer cells. Here, we report a novel function of NRP2 as a regulator...

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Bibliografske podrobnosti
izdano v:Cancer Res
Main Authors: Dutta, Samikshan, Roy, Sohini, Polavaram, Navatha Shree, Stanton, Marissa J., Zhang, Heyu, Bhola, Tanvi, Hönscheid, Pia, Donohue, Terrence M., Band, Hamid, Batra, Surinder K., Muders, Michael H., Datta, Kaustubh
Format: Artigo
Jezik:Inglês
Izdano: 2015
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715955/
https://ncbi.nlm.nih.gov/pubmed/26560516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-1488
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