Tissue plasminogen activator followed by antioxidant-loaded nanoparticle delivery promotes activation/mobilization of progenitor cells in infarcted rat brain

Inherent neuronal and circulating progenitor cells play important roles in facilitating neuronal and functional recovery post stroke. However, this endogenous repair process is rather limited, primarily due to unfavorable conditions in the infarcted brain involving reactive oxygen species (ROS)-medi...

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Publicado en:Biomaterials
Main Authors: Petro, Marianne, Jaffer, Hayder, Yang, Jun, Kabu, Shushi, Morris, Viola B., Labhasetwar, Vinod
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715952/
https://ncbi.nlm.nih.gov/pubmed/26735970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.12.009
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