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Imaging, biodistribution, and dosimetry of radionuclide-labeled PD-L1 antibody in an immunocompetent mouse model of breast cancer

The programmed cell death ligand 1 (PD-L1) participates in an immune checkpoint system involved in preventing autoimmunity. PD-L1 is expressed on tumor cells, tumor-associated macrophages, and other cells in the tumor microenvironment. Anti-PD-L1 antibodies are active against a variety of cancers, a...

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Podrobná bibliografie
Vydáno v:Cancer Res
Hlavní autoři: Josefsson, Anders, Nedrow, Jessie R., Park, Sunju, Banerjee, Sangeeta Ray, Rittenbach, Andrew, Jammes, Fabien, Tsui, Benjamin, Sgouros, George
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715915/
https://ncbi.nlm.nih.gov/pubmed/26554829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-2141
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