Striatal Fos expression is indicative of dopamine D1/D2 synergism and receptor supersensitivity.
Immediate-early genes, such as c-fos, are responsive to dopaminergic stimulation in the brain and can have prolonged effects on the transcription of other genes. Thus, they may mediate some of the long-term consequences of altered dopaminergic transmission on striatal neurons, such as the supersensi...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47159/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8102797/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.16.7451 |
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