Targeted Exome Sequencing Profiles Genetic Alterations in Leiomyosarcoma

Leiomyosarcoma (LMS) belongs to the class of genetically complex sarcomas and shows numerous, often non-recurrent chromosomal imbalances and aberrations. We investigated a group of LMS using NGS platform to identify recurrent genetic abnormalities and possible therapeutic targets. Targeted exome seq...

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Bibliografiske detaljer
Udgivet i:Genes Chromosomes Cancer
Main Authors: Agaram, Narasimhan P, Zhang, Lei, LeLoarer, Francois, Silk, Tarik, Sung, Yun-Shao, Scott, Sasinya N., Kuk, Deborah, Qin, Li-Xuan, Berger, Michael F., Antonescu, Cristina R, Singer, Samuel
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715662/
https://ncbi.nlm.nih.gov/pubmed/26541895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22318
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