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Multiple SNP-sets Analysis for Genome-wide Association Studies through Bayesian Latent Variable Selection

The power of genome-wide association studies (GWAS) for mapping complex traits with single SNP analysis may be undermined by modest SNP effect sizes, unobserved causal SNPs, correlation among adjacent SNPs, and SNP-SNP interactions. Alternative approaches for testing the association between a single...

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Vydáno v:Genet Epidemiol
Hlavní autoři: Lu, Zhaohua, Zhu, Hongtu, Knickmeyer, Rebecca C, Sullivan, Patrick F., Stephanie, Williams N., Zou, Fei
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715655/
https://ncbi.nlm.nih.gov/pubmed/26515609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21932
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