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Predictions for Proteins, RNAs and DNAs with the Gaussian Dielectric Function Using DelPhiPKa

We developed a Poisson-Boltzmann based approach to calculate the PK(a) values of protein ionizable residues (Glu, Asp, His, Lys and Arg), nucleotides of RNA and single stranded DNA. Two novel features were utilized: the dielectric properties of the macromolecules and water phase were modeled via the...

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Detalhes bibliográficos
Publicado no:Proteins
Main Authors: Wang, Lin, Li, Lin, Alexov, Emil
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715546/
https://ncbi.nlm.nih.gov/pubmed/26408449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24935
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