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Acute TrkB-inhibition rescues phenobarbital-resistant seizures in a mouse model of neonatal ischemia

Neonatal seizures are commonly associated with hypoxic-ischemic encephalopathy. Phenobarbital (PB)-resistance is common and poses a serious challenge in clinical management. Using a newly characterized neonatal mouse model of ischemic seizures, this study investigated a novel strategy to rescue PB-r...

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Bibliografiske detaljer
Udgivet i:Eur J Neurosci
Main Authors: Kang, SK., Johnston, MV., Kadam, SD.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715496/
https://ncbi.nlm.nih.gov/pubmed/26452067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.13094
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