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New Dynamic Rotamer Libraries: Data-Driven Analysis of Side-Chain Conformational Propensities

Most rotamer libraries are generated from subsets of the PDB and do not fully represent the conformational scope of protein side chains. Previous attempts to rectify this sparse coverage of conformational space have involved application of weighting and smoothing functions. We resolve these limitati...

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Detalhes bibliográficos
Publicado no:Structure
Main Authors: Towse, Clare-Louise, Rysavy, Steven J., Vulovic, Ivan M., Daggett, Valerie
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715459/
https://ncbi.nlm.nih.gov/pubmed/26745530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.10.017
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