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New Dynamic Rotamer Libraries: Data-Driven Analysis of Side-Chain Conformational Propensities

Most rotamer libraries are generated from subsets of the PDB and do not fully represent the conformational scope of protein side chains. Previous attempts to rectify this sparse coverage of conformational space have involved application of weighting and smoothing functions. We resolve these limitati...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Structure
Asıl Yazarlar: Towse, Clare-Louise, Rysavy, Steven J., Vulovic, Ivan M., Daggett, Valerie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715459/
https://ncbi.nlm.nih.gov/pubmed/26745530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.10.017
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