Probable impact of age and hypoxia on proliferation and microRNA expression profile of bone marrow-derived human mesenchymal stem cells

Decline in the therapeutic potential of bone marrow-derived mesenchymal stem cells (MSC) is often seen with older donors as compared to young. Although hypoxia is known as an approach to improve the therapeutic potential of MSC in term of cell proliferation and differentiation capacity, its effects...

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Bibliografske podrobnosti
izdano v:PeerJ
Main Authors: Mohd Ali, Norlaily, Boo, Lily, Yeap, Swee Keong, Ky, Huynh, Satharasinghe, Dilan A., Liew, Woan Charn, Ong, Han Kiat, Cheong, Soon Keng, Kamarul, Tunku
Format: Artigo
Jezik:Inglês
Izdano: PeerJ Inc. 2016
Teme:
Cell Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715434/
https://ncbi.nlm.nih.gov/pubmed/26788424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.1536
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