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Characterization of Deletions of the HBA and HBB Loci by Array Comparative Genomic Hybridization

Thalassemia is among the most common genetic diseases worldwide. α-Thalassemia is usually caused by deletion of one or more of the duplicated HBA genes on chromosome 16. In contrast, most β-thalassemia results from point mutations that decrease or eliminate expression of the HBB gene on chromosome 1...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Mol Diagn
मुख्य लेखकों: Sabath, Daniel E., Bender, Michael A., Sankaran, Vijay G., Vamos, Esther, Kentsis, Alex, Yi, Hye-Son, Greisman, Harvey A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Investigative Pathology 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715224/
https://ncbi.nlm.nih.gov/pubmed/26612711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2015.07.011
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