The Neuroprotective Effect of Rapamycin as a Modulator of the mTOR-NF-κB Axis during Retinal Inflammation

PURPOSE: The determination of the molecular mechanism underlying retinal pathogenesis and visual dysfunction during innate inflammation, and the treatment effect of rapamycin thereon. METHODS: The endotoxin-induced uveitis and retinitis mouse model was established by injecting lipopolysaccharide. Th...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Okamoto, Tomohiro, Ozawa, Yoko, Kamoshita, Mamoru, Osada, Hideto, Toda, Eriko, Kurihara, Toshihide, Nagai, Norihiro, Umezawa, Kazuo, Tsubota, Kazuo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714903/
https://ncbi.nlm.nih.gov/pubmed/26771918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146517
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