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Excessive cocaine use results from decreased phasic dopamine signaling in the striatum
Drug addiction is a neuropsychiatric disorder marked by escalating drug use. Dopamine neurotransmission in the ventromedial striatum (VMS) mediates acute reinforcing effects of abused drugs, but with protracted use the dorsolateral striatum (DLS) is thought to assume control over drug seeking. We me...
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Publicado no: | Nat Neurosci |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4714770/ https://ncbi.nlm.nih.gov/pubmed/24705184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3694 |
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