Reprimo (RPRM) Is a Novel Tumor Suppressor in Pituitary Tumors and Regulates Survival, Proliferation, and Tumorigenicity

Reprimo (RPRM), initially identified as a downstream effector of p53-induced cell cycle arrest at G(2)/M, is a putative tumor suppressor silenced in some types of cancer. In microarrays, the RPRM transcript was repressed 26-fold in gonadotrope (null cell) human pituitary tumors compared with normal...

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Dettagli Bibliografici
Pubblicato in:Endocrinology
Autori principali: Xu, Mei, Knox, Aaron J., Michaelis, Katherine A., Kiseljak-Vassiliades, Katja, Kleinschmidt-DeMasters, Bette K., Lillehei, Kevin O., Wierman, Margaret E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2012
Soggetti:
Cancer-Oncogenes
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714648/
https://ncbi.nlm.nih.gov/pubmed/22562171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-2021
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