Cytosolic monothiol glutaredoxins function in intracellular iron sensing and trafficking via their bound iron-sulfur cluster

Iron is an essential nutrient for cells. It is unknown how iron, after its import into the cytosol, is specifically delivered to iron-dependent processes in various cellular compartments. Here, we identify an essential function of the conserved cytosolic monothiol glutaredoxins Grx3 and Grx4 in intr...

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Pubblicato in:Cell Metab
Autori principali: Mühlenhoff, Ulrich, Molik, Sabine, Godoy, José R., Uzarska, Marta A., Richter, Nadine, Seubert, Andreas, Zhang, Yan, Stubbe, JoAnne, Pierrel, Fabien, Herrero, Enrique, Lillig, Christopher Horst, Lill, Roland
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714545/
https://ncbi.nlm.nih.gov/pubmed/20889129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2010.08.001
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