1α,25-Dihydroxyvitamin D(3) Regulates Mitochondrial Oxygen Consumption and Dynamics in Human Skeletal Muscle Cells

Muscle weakness and myopathy are observed in vitamin D deficiency and chronic renal failure, where concentrations of the active vitamin D(3) metabolite, 1α,25-dihydroxyvitamin D(3) (1α,25(OH)(2)D(3)), are low. To evaluate the mechanism of action of 1α,25(OH)(2)D(3) in skeletal muscle, we examined mi...

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Vydáno v:J Biol Chem
Hlavní autoři: Ryan, Zachary C., Craig, Theodore A., Folmes, Clifford D., Wang, Xuewei, Lanza, Ian R., Schaible, Niccole S., Salisbury, Jeffrey L., Nair, K. Sreekumaran, Terzic, Andre, Sieck, Gary C., Kumar, Rajiv
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714233/
https://ncbi.nlm.nih.gov/pubmed/26601949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.684399
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