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Targeting the leukemia–stroma interaction in acute myeloid leukemia: rationale and latest evidence

The concept of ‘niche’ has become a focus of attention in hematologic malignancies including acute myeloid leukemia (AML). Similar to normal hematopoietic stem cells, AML cells interact both anatomically and functionally with the stroma within the marrow microenvironment. These interactions have a c...

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Detalhes bibliográficos
Publicado no:Ther Adv Hematol
Main Authors: Rashidi, Armin, DiPersio, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713889/
https://ncbi.nlm.nih.gov/pubmed/26834953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620715619307
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