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Ca(2+) leakage out of the sarcoplasmic reticulum is increased in type I skeletal muscle fibres in aged humans

The amount of Ca(2+) stored in the sarcoplasmic reticulum (SR) of muscle fibres is decreased in aged individuals, and an important question is whether this results from increased Ca(2+) leakage out through the Ca(2+) release channels (ryanodine receptors; RyRs). The present study examined the effect...

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Bibliografiske detaljer
Udgivet i:J Physiol
Main Authors: Lamboley, C. R., Wyckelsma, V. L., McKenna, M. J., Murphy, R. M., Lamb, G. D.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713735/
https://ncbi.nlm.nih.gov/pubmed/26574292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271382
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