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Matrine inhibited proliferation and increased apoptosis in human breast cancer MCF-7 cells via upregulation of Bax and downregulation of Bcl-2

Purpose: The aim of the present study was to investigate the effects of matrine on proliferation and apoptosis in human breast cancer MCF-7 cells and its relevant molecular mechanisms. Methods: Breast carcinoma cell line MCF-7 was cultured with series concentrations of Matrine in vitro. The prolifer...

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Détails bibliographiques
Publié dans:Int J Clin Exp Pathol
Auteurs principaux: Li, Haijun, Li, Xiujuan, Bai, Meiling, Suo, Yueer, Zhang, Guohui, Cao, Xueyuan
Format: Artigo
Langue:Inglês
Publié: e-Century Publishing Corporation 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713592/
https://ncbi.nlm.nih.gov/pubmed/26823806
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